|
KMID : 1191420100090020039
|
|
Korean Journal of Optometry and Vision Science
2010 Volume.9 No. 2 p.39 ~ p.43
|
|
|
Factors Affecting the Vitreous Reflux after Intravitreal Injection
|
|
Jee Dong-Hyun
Kim Bo-Yun
La Tae-Yoon
|
|
|
Abstract
|
|
|
Purpose: To analyze the factors affecting the vitreous reflux after intravitreal (IV) injection.
Methods: A prospective study was conducted for 122 eyes of 122 patients who had undergone intravitreal Bevacizumab (Avastinⓡ) injection. The amount of vitreal reflux was measured as the conjunctival blebs size by using caliper after IV injection. We investigated the pre-injection IOP, status of lens, injection technique, and speed of needle removal as risk factors and analyzed the factors affecting the vitreous reflux after IV injection by multivariate linear regression test.
Results: There was no statistically significant correlation between pre-injection IOP and mean conjunctival bleb size (CBS) (p=0.084). The relationship between mean conjunctival bleb size and lens status was not statistically significant, (1.95±1.84 mm) in phakic eyes and (2.18±1.66 mm) in pseudophakic eyes (p=0.723). The relationship between mean CBS and injection technique was statistically significant (p=0.004). The mean CBS was less with the tunneled scleral injection (1.87±1.80 mm) than in eyes undergoing the straight scleral injection (2.03±1.80 mm). Also the mean CBS was statistically less with the slow group of needle removal (1.54±1.58 mm) than in eyes undergoing the fast group of needle removal (3.36±1.70 mm) (p＜0.001).
Conclusions: Slow removal of needle and the tunneled scleral incision can be expected to decrease the vitreal reflux after intravitreal injection.
|
|
|
KEYWORD
|
|
|
Injection technique, Intravitreal injection, Pre-injection IOP, Speed of needle removal, Vitreal reflux
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|